USP5-IN-1
Product Specifications
Target
DUB
Related Pathways
Ubiquitination, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9976
Bioactivity
USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor that binds to the USP5 ZnF-UBD with a KD of 2.8 μM and is selective over nine proteins containing structurally similar ZnF-UBD domains. Additionally, USP5-IN-1 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate [1].
Smiles
O=C(O)CNC(=O)C1=CC=C(S(=O)(=O)N2CCC(C3=CC=C(Cl)C=C3)CC2)C=N1
Molecular Formula
C19H20ClN3O5S
Molecular Weight
437.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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