Anti-Monkey/Human CD40L/CD154 Antibody (5C8)

Anti-Monkey/Human CD40L/CD154 Antibody (5C8) is a mouse-derived IgG2a type antibody inhibitor, targeting to monkey/human CD40L/CD154. Anti-Monkey/Human CD40L/CD154 Antibody (5C8) blocks the interactionbetween CD154 and CD40. Anti-Monkey/Human CD40L/CD154 Antibody (5C8) can be used for the researches of inflammation and immunology, such as colitis and transplant[1][2].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Target

TNF Receptor

Type

Inhibitory Antibodies

Related Pathways

Apoptosis

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-monkey-human-cd40l-cd154-antibody-5c8.html

Purity

99.62

Solubility

10 mM in DMSO

Smiles

[Anti-Monkey/HumanCD40L/CD154Antibody(5C8)]

Molecular Weight

(150 kDa)

References & Citations

[1]Kirk AD, et al. CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc Natl Acad Sci U S A. 1997 Aug 5;94 (16) :8789-94.|[2]Liu Z, et al. Prevention of experimental colitis in SCID mice reconstituted with CD45RBhigh CD4+ T cells by blocking the CD40-CD154 interactions. J Immunol. 2000 Jun 1;164 (11) :6005-14.