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Meclizine

Product Specifications

CAS Number

569-65-3

Target

Apoptosis, Histamine Receptor

Related Pathways

GPCR/G Protein, Apoptosis, Immunology/Inflammation, Neuroscience

Purity

0.9955

Bioactivity

Meclizine, also known as Meclozine, is a piperazine class H1 antagonist with antihistamine properties that inhibits the interaction of histamine at H1 receptors reversibly. It serves as an effective anti-motion sickness agent, able to cross the blood-brain barrier. Additionally, Meclizine acts as an agonist ligand for the mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR, making it useful in research on polyQ toxicity disorders, including Huntington's disease.

Smiles

Cc1cccc(CN2CCN(CC2)C(c2ccccc2)c2ccc(Cl)cc2)c1

Molecular Formula

C25H27ClN2

Molecular Weight

390.95

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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