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Elomotecan hydrochloride

Product Specifications

CAS Number

220997-99-9

Target

Others, Topoisomerase

Related Pathways

DNA Damage/DNA Repair, Others

Bioactivity

Elomotecan hydrochloride (BN 80927), a camptothecin analog from the homocamptothecin family (hCPT), is a highly potent inhibitor of both topoisomerases I and II. It demonstrates superior efficacy in reducing the proliferation of various tumor cells compared to other reference anticancer drugs targeting these topoisomerases.

Smiles

Cl.CC[C@@]1(O)CC(=O)OCc2c1cc1-c3nc4cc(Cl)c(C)cc4c(CN4CCC(C)CC4)c3Cn1c2=O

Molecular Formula

C29H33Cl2N3O4

Molecular Weight

558.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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