APC Anti-Human CD32 Antibody[IV-3]
Product Specifications
Background
CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform) .
Abbreviation
CD32
Gene ID
2212
UniProt
P31994
Host
Mouse
Reactivity
Human
Target
IGFR2; CD32; CDw32; FCG2; FCGR2B; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; IgG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-b
Clonality
Monoclonal
Clone
IV-3
Conjugation
APC
Applications
FCM
Field of Research
Immunology; Innate Immunity
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG2b, κ
Available Sizes
Documents
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