CAY10719
Product Specifications
CAS Number
1942919-63-2
Target
Others, BCRP
Related Pathways
Others, Membrane transporter/Ion channel
Bioactivity
CAY10719 is a selective inhibitor of the breast cancer resistance protein ABCG2 (IC50 = 0.23 μM) with little activity at ABCG1. It has been shown to reverse the ABCG2-mediated resistance toward SN 38 and to inhibit ATPase activity.
Smiles
C(=O)(N1C(C2=C(C=3C(N2)=CC=CC3)CC1)C4=CC(Cl)=C(Cl)C=C4)C5=CC=C(OC)C=C5
Molecular Formula
C25H20Cl2N2O2
Molecular Weight
451.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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