Bengamide B
Product Specifications
CAS Number
104947-69-5
Target
NF-κB, Interleukin, Others
Related Pathways
Others, NF-κB, Immunology/Inflammation
Bioactivity
Potent inhibitor of NF-κB activation (IC50 = 85 nM) ; decreases IκBα phosphorylation. Attenuates LPS-induced nitric oxide production and expression of TNF-α, IL-6 and MCP. Suppresses proliferation of HeLa and HCT116 cells. Anti-inflammatory and antitumor.
Smiles
CCCCCCCCCCCCCC(=O)O[C@H]1CC[C@H](NC(=O)[C@H](OC)[C@H](O)[C@@H](O)[C@H](O)\C=C\C(C)C)C(=O)N(C)C1
Molecular Formula
C32H58N2O8
Molecular Weight
598.81
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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