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Herboxidiene

Product Specifications

CAS Number

142861-00-5

Target

DNA/RNA Synthesis

Related Pathways

DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

Bioactivity

Herboxidiene (GEX1A) is a plant-toxic polyketide compound isolated from Streptomyces ATCC 49982, with herbicidal, cholesterol-lowering, and anticancer activities. It exhibits anti-angiogenic activity by downregulating vascular endothelial growth factor receptor-2 (VEGFR-2) and hypoxia-inducible factor-1? (HIF-1?) .

Smiles

[C@H]([C@H]([C@@H](C)O)OC)(C)[C@@]1([C@](C[C@@H](/C=C/C=C(\C)/[C@H]2O[C@@H](CC(O)=O)CC[C@@H]2C)C)(C)O1)[H]

Molecular Formula

C25H42O6

Molecular Weight

438.6

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/BF2C20DF-C0C4-4F88-87B6-B72227DBFDC8/T36749

Available Sizes

Curated Selection

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