CAY10730
Product Specifications
CAS Number
2206677-06-5
Target
Others
Related Pathways
Others
Bioactivity
CAY10730 is a turn-on fluorescent probe for the detection of nitroreductase activity, a marker of hypoxia. In the presence of nitroreductase, CAY10730 is transformed into a highly fluorescent molecule that displays excitation/emission maxima of 454/520 nm, respectively. It is selective for nitroreductase over a variety of bioanalytes, including glutathione, ascorbic acid, and reactive oxygen species such as H2O2. CAY10730 (1 μM) has been used to detect hypoxia in A549 human lung carcinoma cells.
Smiles
COc1ccc2c(Oc3cc(OCc4ccc(cc4)N(=O)=O)ccc3C22OC(=O)c3ccccc23)c1
Molecular Formula
C28H19NO7
Molecular Weight
481.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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