Activated protein C
Activated protein C is an anticoagulant targeting coagulation factors Va and VIIIa. Activated protein C demonstrates cytoprotective effects through binding to endothelial cell protein C receptor (EPCR) and protease-activated receptor-1 (PAR-1), regulating gene expression, anti-inflammation, anti-apoptosis, and stabilizing endothelial barriers. Activated protein C is promising for research of diseases such as severe sepsis and ischemic stroke[1].
Product Specifications
CAS Number
42617-41-4
UNSPSC
12352204
Target
Factor Xa; Protease Activated Receptor (PAR)
Type
Enzyme
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/activated-protein-c.html
Purity
0
Solubility
10 mM in DMSO
Smiles
[ActivatedproteinC]
References & Citations
[1]Griffin JH, et al. Activated protein C. J Thromb Haemost. 2007 Jul;5 Suppl 1:73-80.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
2- ((4-bromophenyl) sulfonyl) -3- ((4- (3- (trifluoromethyl) phenoxy) phenyl) amino) prop-2-enenitrile