Osimertinib mesylate
Product Specifications
CAS Number
1421373-66-1
Target
EGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Purity
>99.99%
Bioactivity
Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib mesylate has antitumor activity for the treatment of EGFR-mutated non-small-cell lung cancer.
Smiles
CS(O)(=O)=O.COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12
Molecular Formula
C29H37N7O5S
Molecular Weight
595.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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