2,3-dinor Thromboxane B1
Product Specifications
CAS Number
196493-76-2
Target
Others, Prostaglandin Receptor
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Others
Bioactivity
Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. In rats and rabbits, 2,3-dinor TXB1 has been identified as another urinary metabolite of TXB2. However in human urine, only trace amounts of 2,3-dinor TXB1 have been identified. In rats, 2,3-dinor TXB1 is excreted at a much higher rate than 2,3-dinor TXB2 (19.2 ± 4.9 ng/24 hr and 1.6 ± 0.3 ng/24 hr, respectively) . Therefore, urinary 2,3-dinor TXB1 is a suitable marker of thromboxane biosynthesis in rats.
Smiles
CCCCC[C@H](O)\C=C\[C@H]1OC(O)C[C@H](O)[C@@H]1CCCCC(O)=O
Molecular Formula
C18H32O6
Molecular Weight
344.448
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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