BRD-8000.3
Product Specifications
CAS Number
2365504-95-4
Target
Antibiotic
Related Pathways
Microbiology/Virology
Purity
0.9978
Bioactivity
BRD-8000.3 is a narrow-spectrum, bactericidal antimycobacterial agent that specifically inhibits EfpA, specifically designed to kill drug-tolerant Mtb.Study revealed BRD-8000.3 at resolutions of 2.9 Å and 3.4 Å, resp, EfpA forms an antiparallel dimer. Functional studies reveal that EfpA is a lipid transporter and BRD-8000.3 inhibits its lipid transport activity.
Smiles
C(NC=1N=C(Br)C(=CC1)C=2N=CC=CN2)(=O)[C@H]3[C@H](C=C(C)C)C3(C)C
Molecular Formula
C19H21BrN4O
Molecular Weight
401.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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