5-Benzyloxygramine
Product Specifications
CAS Number
1453-97-0
Target
5-HT Receptor, Dopamine Receptor, Antibiotic
Related Pathways
Microbiology/Virology, Neuroscience, GPCR/G Protein
Purity
0.9913
Bioactivity
5-Benzyloxygramine is an N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities. It stabilizes the N-NTD dimers through simultaneous hydrophobic interactions with both partners, resulting in abnormal N protein oligomerization, which was further confirmed in cell studies[1]. [1]. Shan-Meng Lin, et al. Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design. J Med Chem. 2020 Mar 26;63 (6) :3131-3141.
Smiles
CN(C)Cc1c[nH]c2ccc(OCc3ccccc3)cc12
Molecular Formula
C18H20N2O
Molecular Weight
280.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
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