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19-O-Acetylchaetoglobosin A

Product Specifications

CAS Number

50939-69-0

Target

Others, Arp2/3 Complex

Related Pathways

Cytoskeletal Signaling, Others

Bioactivity

19-O-Acetylchaetoglobosin A is a fungal metabolite originally isolated fromC. globosumthat has actin polymerization inhibitory and cytotoxic activities.1,2It inhibits actin polymerization in a cell-free assay when used at a concentration of 2 μM.219-O-Acetylchaetoglobosin A (3.2, 10, and 32 μg/ml) is cytotoxic to HeLa cervical cancer cells.1

Smiles

C[C@H]1C2[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@]22[C@@H](\C=C/C[C@H](C)\C=C(C)/[C@@H](OC(C)=O)C(=O)\C=C/C2=O)[C@@H]2O[C@]12C

Molecular Formula

C34H38N2O6

Molecular Weight

570.686

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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