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(±) 17-HETE

Product Specifications

CAS Number

128914-47-6

Target

Others, ATPase, Cytochromes P450

Related Pathways

Metabolism, Membrane transporter/Ion channel, Others

Bioactivity

Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±) 17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 μM the (S) -enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R) -isomer is inactive.

Smiles

CCCC(O)C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O

Molecular Formula

C20H32O3

Molecular Weight

320.473

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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