Naldemedine
Product Specifications
CAS Number
916072-89-4
Target
Others|||Opioid Receptor
Related Pathways
GPCR/G Protein|||Endocrinology/Hormones|||Others|||Neuroscience
Bioactivity
Naldemedine (S 297995) is a peripheral selective ?-opioid receptor antagonist being developed by Shionogi for the treatment of opioid-induced adverse reactions, including constipation, nausea, and vomiting. They are usually well tolerated, mainly with mild to moderate gastrointestinal side effects.
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O[C@]12[C@@]34C=5C(O[C@]3(C(O)=C(C(NC(C)(C)C6=NC(=NO6)C7=CC=CC=C7)=O)C1)[H])=C(O)C=CC5C[C@]2(N(CC8CC8)CC4)[H]
Molecular Formula
C32H34N4O6
Molecular Weight
570.64
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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