Dihydrocompactin

Dihydrocompactin, an antifungal metabolite, is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase (HMG-CoA reductase) from Penicillium citrinum[1].

Product Specifications

CAS Number

[78366-44-6]

UNSPSC

12352005

Target

Antibiotic; Fungal; HMG-CoA Reductase (HMGCR)

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection; Inflammation/Immunology

Smiles

O[C@@H](CC(O1)=O)C[C@H]1CC[C@@H]2[C@@]3([H])[C@H](CCC[C@]3([H])C=C[C@@H]2C)OC([C@@H](C)CC)=O

Molecular Formula

C23H36O5

Molecular Weight

392.53

References & Citations

[1]Y K Lam, et al. Dihydrocompactin, a new potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase from Penicillium citrinum. J Antibiot (Tokyo) . 1981 May;34 (5) :614-6.