Coralyne chloride
Product Specifications
CAS Number
38989-38-7
Target
Topoisomerase
Related Pathways
DNA Damage/DNA Repair
Purity
0.9935
Bioactivity
Coralyne chloride is a protoberberine with strong anticancer activity. It can be used to prepare Coralyne derivatives, a fluorescent DNA-based molecular rectifier built into DNA duplexes through site-specific insertion. It acts as a topoisomerase I toxic molecule, inducing topoisomerase I-mediated DNA cleavage.
Smiles
[Cl-].COc1cc2cc[n+]3c(C)c4cc(OC)c(OC)cc4cc3c2cc1OC
Molecular Formula
C22H22ClNO4
Molecular Weight
399.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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