Ruxolitinib phosphate
Product Specifications
CAS Number
1092939-17-7
Target
Autophagy, Mitophagy, JAK
Related Pathways
Stem Cells, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Autophagy, Angiogenesis
Purity
>99.99%
Bioactivity
Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Its selectivity for JAK1/2 is more than 130 times that of JAK3.
Smiles
OP(O)(O)=O.N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Molecular Formula
C17H21N6O4P
Molecular Weight
404.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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