Tebuquine
Product Specifications
CAS Number
74129-03-6
Target
Others, Parasite
Related Pathways
Microbiology/Virology, Others
Bioactivity
Tebuquine is an antimalarial agent. Tebuquine is active against P. falciparum in vitro. Tebuquine in vitro shows a chloroquine-like effect, but not in vivo, suggesting that its mode of action in vivo is different from that of chloroquine. Tebuquine has no action in the CIPC in vitro and affects primarily mitochondria of the parasites in vivo. It probably acts through a metabolite. Both pre-erythrocytic and erythrocytic stages of rodent malaria parasites are affected by Tebuquine.
Smiles
N(C=1C2=C(N=CC1)C=C(Cl)C=C2)C3=CC(=C(O)C(CNC(C)(C)C)=C3)C4=CC=C(Cl)C=C4
Molecular Formula
C26H25Cl2N3O
Molecular Weight
466.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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