LEI-101
Product Specifications
CAS Number
1228660-00-1
Target
Others, Cannabinoid Receptor
Related Pathways
GPCR/G Protein, Others
Bioactivity
LEI-101 is a potent, selective, and orally bioavailable cannabinoid CB2 receptor agonist, with a pEC50 of 8 for hCB2, and a pKi of less than 4 for hERG. LEI-101 is approximately 100-fold more potent in binding to CB2 receptors than to CB1 receptors. It has therapeutic potential in diseases associated with inflammation and/or oxidative stress, including kidney disease [1] [2].
Smiles
O=C1N(C(=O)CN1CC2=CC=C(C=C2)C=3N=C(CN4CCS(=O)(=O)CC4)C(F)=CC3)C5CC5
Molecular Formula
C23H25FN4O4S
Molecular Weight
472.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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