AZ10397767
Product Specifications
CAS Number
333742-63-5
Target
Others, CXCR
Related Pathways
Others, GPCR/G Protein, Autophagy, Immunology/Inflammation
Bioactivity
AZ10397767 is a potent CXCR2 antagonist (IC50 = 1 nM) . AZ10397767 significantly reduced the numbers of infiltrating neutrophils into both in vitro and in vivo tumor models.
Smiles
N([C@@H](CO)C)C1=C2C(=NC(SCC3=C(F)C(Cl)=CC=C3)=N1)NC(=O)S2
Molecular Formula
C15H14ClFN4O2S2
Molecular Weight
400.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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