Recombinant human ST6GAL1 protein
ST6GAL1 also known as Beta-galactoside alpha-2, 6-sialyltransferase isoform a, is a member of glycosyltransferase family 29. This protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. ST6GAL1, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. Recombinant human ST6GAL1, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Beta-galactoside alpha-26-sialyltransferase 1 isoform a, Beta-galactoside alpha-2,6-sialyltransferase 1 isoform a, SIAT1, ST6GalI, ST6N
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
46 kDa (403aa)
Additionnal Information
References & Citations
Kuhn B., et al. (2013) Acta Crystallogr. D Biol. Crystallogr. 69 (PT 9), 1826-1838
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_775323.1
Uniprot Accession Number
P15907
Species
Human
AA Sequence
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