ARN-6039
Product Specifications
CAS Number
1675206-11-7
Target
Others, ROR
Related Pathways
Metabolism, Others
Bioactivity
ARN-6039, an orally available inverse agonist of RORγ, targets Autoimmune Neuroinflammatory Demyelinating Disease. Its efficacy was demonstrated in a RORγ-activated IL-17A Prom/LUCPorter assay in HEK 293 cells (360 nM) and in IL-17 release from CD4+T cell assays (220 nM) .
Smiles
COc1cc2C(=O)C(Cc3ncccc3C(F)(F)F)Cc2cc1N1CCOCC1
Molecular Formula
C21H21F3N2O3
Molecular Weight
406.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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