VUF-10497
Product Specifications
CAS Number
1080623-12-6
Target
Histamine Receptor, Others
Related Pathways
Others, GPCR/G Protein, Immunology/Inflammation, Neuroscience
Bioactivity
VUF-10497 is a histamine H4 receptor inverse agonist (pKi = 7.57) . VUF-10497 was found to possess anti-inflammatory properties in vivo in the rat. VUF-10497 also possesses a considerable affinity for the human histamine H1 receptor.
Smiles
N(CC1=CC=CS1)C=2C3=C(N=C(N2)N4CCN(C)CC4)C=CC(Cl)=C3
Molecular Formula
C18H20ClN5S
Molecular Weight
373.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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