MI-1481
Product Specifications
CAS Number
1887178-64-4
Target
Epigenetic Reader Domain|||Others
Related Pathways
Others|||Chromatin/Epigenetic
Bioactivity
MI-1481 is an effective MML1 inhibitor (IC50: 3.6 nM) . MI-1481 showed very potent inhibition of the menin-MLL1 interaction (IC50: 3.6 nM) . MI-1481 also demonstrates pronounced activity in MLL leukemia cells and in vivo in MLL leukemia models.
Smiles
C(N1C=2C(C=C1C#N)=C(C)C(CN3CCC(NC4=C5C(SC(CC(F)(F)F)=C5)=NC=N4)CC3)=CC2)[C@@H]6CNC(=O)CO6
Molecular Formula
C29H30F3N7O2S
Molecular Weight
597.65
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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