KPC-2-IN-3
Product Specifications
Target
Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
KPC-2-IN-3 (Compound 3b) is a KPC-2 inhibitor with an IC50 of 0.533 ?M and a Ki of 0.194 ?M. It works synergistically with Meropenem to exhibit antibacterial activity against carbapenem-resistant K. pneumoniae K47-25, reducing bacterial count and demonstrating a post-antibiotic effect. Additionally, KPC-2-IN-3 significantly decreases lung bacterial load in a mouse pneumonia model.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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