Avanbulin
Product Specifications
CAS Number
798577-91-0
Target
Others, Microtubule Associated
Related Pathways
Others, Cytoskeletal Signaling
Bioactivity
Avanbulin is a potent inhibitor of tubulin polymerization with antitumor activity. It elicits a unique microtubule (MT) phenotype, distinct from colchicine, paclitaxel, and vinblastine has broad in vitro anti-proliferative activity against a diverse range of human tumor lines at low nM IC50s.
Smiles
Nc1ccc(cc1)C(=O)Cn1c(nc2ccccc12)-c1nonc1NCCC#N
Molecular Formula
C20H17N7O2
Molecular Weight
387.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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