Fimepinostat
Product Specifications
CAS Number
1339928-25-4
Target
PI3K, Apoptosis, HDAC
Related Pathways
PI3K/Akt/mTOR signaling, Apoptosis, DNA Damage/DNA Repair, Chromatin/Epigenetic
Purity
0.9987
Bioactivity
Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, CUDC-907 inhibits the activity of both PI3K class I isoforms and HDAC, thereby preventing the activation of the PI3K-AKT-mTOR signal transduction pathway that is often overactivated in many cancer cell types.
Smiles
COc1ccc(cn1)-c1nc(N2CCOCC2)c2sc(CN(C)c3ncc(cn3)C(=O)NO)cc2n1
Molecular Formula
C23H24N8O4S
Molecular Weight
508.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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