LOM612
Product Specifications
CAS Number
2173232-79-4
Target
FOXO
Related Pathways
Apoptosis
Bioactivity
LOM612 is a potent and specific FOXO relocator that induces nuclear translocation of the FOXO3a reporter protein as well as endogenous FOXO3a and FOXO1 in a dose-dependent manner in U2OS cells, down-regulates the expression of c-Myc and cyclin D1, and has anti-proliferative effects in human cancer cell lines.
Smiles
O=C1C=2SN=C(C2C(=O)C=3C=CC=CC13)N(C)C
Molecular Formula
C13H10N2O2S
Molecular Weight
258.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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