Filgotinib
Product Specifications
CAS Number
1206161-97-8
Target
HIV Protease, JAK, Tyrosine Kinases
Related Pathways
Stem Cells, JAK/STAT signaling, Microbiology/Virology, Angiogenesis, Proteases/Proteasome, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors
Purity
0.9979
Bioactivity
Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 values of 10 nM for JAK1, 28 nM for JAK2, 810 nM for JAK3, and 116 nM for TYK2.
Smiles
O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1
Molecular Formula
C21H23N5O3S
Molecular Weight
425.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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