Cyclic ADP-ribose
Product Specifications
CAS Number
119340-53-3
Target
Endogenous Metabolite|||Calcium Channel|||TRP/TRPV Channel
Related Pathways
Metabolism|||Membrane transporter/Ion channel
Bioactivity
Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger synthesized from NAD+ by ADP-ribosyl cyclase. It mainly increases cytosolic calcium through Ryanodine receptor-mediated endoplasmic reticulum release and extracellular influx via the opening of TRPM2 channels.
Smiles
O[C@H]1[C@@]2(N3C4=C(N=C3)C(=N)N(C=N4)[C@@]5(O[C@@]([C@@H](O)[C@H]5O)(COP(=O)(O)OP(=O)(O)OC[C@@](O2)([C@H]1O)[H])[H])[H])[H]
Molecular Formula
C15H21N5O13P2
Molecular Weight
541.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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