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Vc-MMAD

Product Specifications

CAS Number

1401963-17-4

Target

Microtubule Associated, Drug-Linker Conjugates for ADC

Related Pathways

Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related

Purity

0.9885

Bioactivity

Vc-MMAD, a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), combines the ADC linker Val-Cit (Valine-Citrulline) with the potent tubulin inhibitor MMAD. This compound leverages the targeting capability of ADCs to deliver the cytotoxic agent MMAD specifically to cancer cells, enhancing therapeutic efficacy while minimizing off-target effects.

Smiles

CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(Cc1ccccc1)c1nccs1)OC)N(C)C(=O)C(NC(=O)C(C(C)C)N(C)C(=O)OCc1ccc(NC(=O)C(CCCNC(N)=O)NC(=O)C(NC(=O)CCCCCN2C(=O)C=CC2=O)C(C)C)cc1)C(C)C

Molecular Formula

C70H104N12O14S

Molecular Weight

1369.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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