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Pralnacasan

Product Specifications

CAS Number

192755-52-5

Target

Caspase, Others

Related Pathways

Others, Proteases/Proteasome, Apoptosis

Bioactivity

Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM) . Pralnacasan has the potential for osteoarthritis and rheumatoid arthritis treatment.

Smiles

CCO[C@@H]1OC(=O)C[C@@H]1NC(=O)[C@@H]1CCCN2N1C(=O)[C@H](CCC2=O)NC(=O)c1nccc2ccccc12

Molecular Formula

C26H29N5O7

Molecular Weight

523.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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