Incyclinide
Product Specifications
CAS Number
15866-90-7
Target
MMP
Related Pathways
Proteases/Proteasome
Purity
0.9799
Bioactivity
Chemically modified tetracyclines (CMTs) can inhibit MMPs, but lack antimicrobial activity. Nonantimicrobial derivative of tetracycline called incyclinide (COL-3, CMT-3) . Incyclinide (CMT-3) has been shown to experimentally suppress prostate cancer, colon adenocarcinoma and melanoma invasiveness in cell culture and to inhibit tumor growth and metastasis.
Smiles
[H][C@@]12Cc3cccc(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)C[C@]1([H])C2
Molecular Formula
C19H17NO7
Molecular Weight
371.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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