AZD5582
Product Specifications
CAS Number
1258392-53-8
Target
Apoptosis, IAP
Related Pathways
Apoptosis
Purity
>99.99%
Bioactivity
AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.
Smiles
OC(=O)C(F)(F)F.CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1[C@@H](Cc2ccccc12)OCC#CC#CCO[C@@H]1Cc2ccccc2[C@@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C1CCCCC1
Molecular Formula
C58H78N8O8
Molecular Weight
1015.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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