A-443654
Product Specifications
CAS Number
552325-16-3
Target
PKA, PKC, Src, Chk, VEGFR, Akt, FLT, Casein Kinase, ERK, MAPK, GSK-3, S6 Kinase, CDK
Related Pathways
Cell Cycle/Checkpoint, Stem Cells, MAPK, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Angiogenesis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Metabolism
Purity
0.9951
Bioactivity
A-443654, a pan-Akt inhibitor, exhibits equal potency against Akt1, Akt2, and Akt3 within cells (Ki=160 pM) .
Smiles
C([C@@H](COC=1C=C(C=NC1)C=2C=C3C(=CC2)NN=C3C)N)C=4C=5C(NC4)=CC=CC5
Molecular Formula
C24H23N5O
Molecular Weight
397.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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