GATA4-NKX2-5-IN-1
Product Specifications
CAS Number
544681-96-1
Target
Others, IKZF
Related Pathways
Immunology/Inflammation, Others
Purity
0.99
Bioactivity
GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression.GATA4-NKX2-5-IN-1 dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM.
Smiles
C(NC1=CC=C(N(CC)CC)C=C1)(=O)C=2C(=NOC2C)C3=CC=CC=C3
Molecular Formula
C21H23N3O2
Molecular Weight
349.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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