Quabodepistat
Quabodepistat (OPC-167832) is a potent and orally active dprE1 inhibitor with an IC50 of 0.258 μM. Quabodepistat has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1].
Product Specifications
CAS Number
1883747-71-4
Product Name Alternative
OPC-167832
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/quabodepistat.html
Purity
98.00
Solubility
DMSO : 180 mg/mL (ultrasonic)
Smiles
O=C1NC2=C(C(OC[C@@]3(O)[C@H](O)CN(C4=C(F)C=C(Cl)C=C4F)CC3)=CC=C2F)CC1
Molecular Formula
C21H20ClF3N2O4
Molecular Weight
456.84
References & Citations
[1]Norimitsu Hariguchi, et al. OPC-167832, a Novel Carbostyril Derivative with Potent Antituberculosis Activity as a DprE1 Inhibitor.Antimicrob Agents Chemother. 2020 May 21;64 (6) :e02020-19.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K0725102 1.0 µg DNA
FAM55A sgRNA CRISPR Lentivector (Human) (Target 1)
Sign In for Pricing
View Details 
GTR15146628 1 Vial
Lentiviral mouse Csta1 shRNA (UAS) - Lentiviral mouse Csta1 shRNA (UAS, RFP) (100)
Sign In for Pricing
View Details