(R) -Atuveciclib
Product Specifications
CAS Number
2923012-24-0
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
(R) -Atuveciclib is an isomer of Atuveciclib. Atuveciclib (BAY 1143572) is a potent and highly selective PTEFb/CDK9 inhibitor with an IC50 value of 13 nm for CDK9/CycT1 and a selectivity ratio of 100 for CDK2, with highly bioavailable and orally available advantages.
Smiles
O(C)C1=C(C=CC(F)=C1)C=2N=C(NC3=CC(CS(C)(=N)=O)=CC=C3)N=CN2
Molecular Formula
C18H18FN5O2S
Molecular Weight
387.43
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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