Schisanchinin D

Schisanchinin D is an NO release inhibitor found in the fruits of Schisandra chinensis. Schisanchinin D can inhibit the release of nitric oxide (NO) by lipopolysaccharide (LPS) -activated microglia in primary murine BV2 microglia cells. Schisanchinin D is promising for research of neurodegenerative diseases such as Alzheimer's disease (AD) [1][2].

Product Specifications

CAS Number

[1614245-13-4]

UNSPSC

12352005

Target

NO Synthase

Related Pathways

Immunology/Inflammation

Field of Research

Neurological Disease

Smiles

OC1=C(OC)C(OC)=CC2=C1C3=C(OC)C(OC)=C(OC)C=C3C[C@H](C)[C@H](C)C2

Molecular Formula

C23H30O6

Molecular Weight

402.48

References & Citations

[1]Hu D, et al. Dibenzocyclooctadiene lignans from Schisandra chinensis and their inhibitory activity on NO production in lipopolysaccharide-activated microglia cells. Phytochemistry. 2014 Aug;104:72-8.|[2]Jafernik K, et al. Comprehensive review of dibenzocyclooctadiene lignans from the Schisandra genus: anticancer potential, mechanistic insights and future prospects in oncology. Chin Med. 2024 Jan 24;19 (1) :17.