IL-5, murine recombinant

Mouse Interleukin-5 (mIL-5) is a glycoprotein also known as EDF and TRF. It is involved in B-cell growth and eosinophil activation. IL-5 has been shown to be expressed in Th2, mast cells and eosinophils and is regulated by GATA-3, in addition to other transcription factors. IL-5 signals its biological effect through interaction with the IL-5 receptor (IL-5R). Recombinant mIL-5 is produced in E.Coli, comprised of two 113 amino acid chains forming a disulfide-linked homodimer with a molecular weight of 26.2 kDa.