Question 1

What is the catalog number for LY-411575?

Accepted Answer

The catalog number for LY-411575 is 2648-1.

Question 2

Is LY-411575 in stock?

Accepted Answer

LY-411575 is currently made to order / not held in immediate stock. Contact us for lead time.

Question 3

What is LY-411575 used for?

Accepted Answer

LY411575 is a potent, cell-permeable γ-secretase inhibitor (IC₅₀ of 0.078 nM/0.082 nM (membrane/cell-based); also inhibits Notch clevage with with IC₅₀ of 0.39 nM. Notch inhibition using LY-411575 induces cochlear hair cell regeneration and recovery of hearing in mice after acoustic trauma.

Question 4

Is this product tested for endotoxin levels?

Accepted Answer

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Question 5

Can I request additional validation data, such as western blot images, for this product?

Accepted Answer

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

Question 6

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

Accepted Answer

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

LY-411575

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