EPZ-6438
A potent and selective inhibitor of histone methyltransferase EZH2. EPZ-6438 specifically inhibits cellular H3K27 methylation leading to selective apoptotic killing of SMARCB1 mutant MRT cells. It also induces neuronal differentiation and cell cycle inhibition while suppressing expression of Hedgehog (Hh) pathway genes.
Product Specifications
Shipping Conditions
gel pack
Storage Conditions
-20 ̊C
Shelf Life
36 months
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