DCVJ

DCVJ (9- (2,2-Dicyanovinyl) julolidine), a molecular rotor and unique fluorescent dye, binds to tubulin and actin, and increases its fluorescence intensity drastically upon polymerization. DCVJ also binds to phospholipid bilayers and increases its fluorescence intensity. DCVJ can detect the kinetic process of degranulation of mast cells (Absorption/emission=489/505 nm) [1][2].

Product Specifications

CAS Number

[58293-56-4]

Product Name Alternative

9- (2,2-Dicyanovinyl) julolidine

UNSPSC

12171500

Hazard Statement

H301, H319

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dcvj.html

Purity

99.48

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

N#C/C(C#N)=C/C1=CC(CCCN2CCC3)=C2C3=C1

Molecular Formula

C16H15N3

Molecular Weight

249.31

Precautions

H301, H319

References & Citations

[1]Furuno T, et al. A fluorescent molecular rotor probes the kinetic process of degranulation of mast cells. Immunol Lett. 1992;33 (3) :285-288. |[2]Haidekker MA, et al. New fluorescent probes for the measurement of cell membrane viscosity. Chem Biol. 2001 Feb;8 (2) :123-31. |[3]Nagarajan S, et al. Fluorescent Probe DCVJ Shows High Sensitivity for Characterization of Amyloid β-Peptide Early in the Lag Phase. Chembiochem. 2017 Nov 16;18 (22) :2205-2211.