What is the catalog number for 14-3-3 Sigma Antibody?

The catalog number for 14-3-3 Sigma Antibody is orb2641515.

What sizes are available for 14-3-3 Sigma Antibody?

14-3-3 Sigma Antibody is available in the following size(s): 7 mL.

Is 14-3-3 Sigma Antibody in stock?

14-3-3 Sigma Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

14-3-3 Sigma Antibody

SFN (Stratifin), also called 14-3-3 Sigma, is a p53-induced tumor suppressor gene which is activated in response to DNA damage, causing cell cycle arrest at G2 phase by blocking cdc2-cyclin B1 complex from entering the nucleus. It is inactivated in breast, lung, prostate, liver and gastric cancer. It is associated with poor prognosis when its down-regulation is observed in epithelial ovarian cancer. SFN expression could contribute to cancer cell proliferation and the development and/or progression of human gastrointestinal cancer.

Product Specifications

UniProt

P31947

Reactivity

Human

Immunogen

Full length recombinant human protein was used as the immunogen for the 14-3-3 Sigma antibody.

Clonality

Monoclonal

Clone

CPTC-SFN-2

Conjugation

Unconjugated

Purification

Protein G affinity chromatography

Dilution

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

The stated application concentrations are suggested starting points. Titration of the 14-3-3 Sigma antibody may be required due to differences in protocols and secondary/substrate sensitivity.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.