What is the catalog number for Semaxinib?

The catalog number for Semaxinib is T2064.

What sizes are available for Semaxinib?

Semaxinib is available in the following size(s): 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Semaxinib come in?

Semaxinib is available in 6 different pack sizes.

Is Semaxinib in stock?

Semaxinib is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Semaxinib?

Semaxinib is manufactured by Molfinity.

What is the estimated delivery time for Semaxinib?

Estimated delivery time for Semaxinib is approximately 10 business day(s), depending on your location.

Semaxinib

Product Specifications

CAS Number

204005-46-9

Target

VEGFR

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.9984

Bioactivity

Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 μM), exhibiting a 20-fold greater selectivity for VEGFR2 over PDGFRβ, with no activity against InsR, EGFR, and FGFR. Semaxinib reversibly inhibits ATP binding to the tyrosine kinase domain of VEGFR2, potentially inhibiting VEGF-stimulated endothelial cell migration and proliferation, thereby reducing tumor microvasculature.