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Recombinant EpCAM Antibody / Cytoplasmic domain

Epithelial cellular adhesion molecule (Ep-CAM), also called epithelial specific antigen (ESA), is a 40-43kDa transmembrane epithelial glycoprotein. It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. Antibody to Ep-CAM has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Product Specifications

UniProt

P16422

Reactivity

Human

Immunogen

A portion of amino acids 289-314 of human EpCAM was used as the immunogen for the recombinant EpCAM antibody.

Clonality

Recombinant

Clone

EGP40/7035R

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Protein A affinity

Dilution

Immunohistochemistry (FFPE) : 1-2ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the recombinant EpCAM antibody should be determined by the researcher.

Tested Applications

IHC-P

Host or Source

Rabbit

Preservative

1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

Isotype

Rabbit IgG, kappa

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