Epi-cryptoacetalide

Epi-cryptoacetalide is a natural diterpenoid. Epi-cryptoacetalide reveals high affinity to ER-α and PGE2 receptor (EP2 subtype) with Ki values of 0.3 μM and 1.92 μM, respectively. Epi-cryptoacetalide has anti-endometriosis activities[1].

Product Specifications

CAS Number

[132152-57-9]

UNSPSC

12352005

Target

Estrogen Receptor/ERR; Prostaglandin Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/epi-cryptoacetalide.html

Solubility

10 mM in DMSO

Smiles

O=C1O[C@@]2(OC[C@@H](C2)C)C3=CC=C(C(C)(CCC4)C)C4=C31

Molecular Formula

C18H22O3

Molecular Weight

286.37

References & Citations

[1]Herbert Situmorang, et al. IN-SILICO dynamic analysis of Sulawesi propolis as anti-endometriosis drug: Interaction study with TNF alpha receptor, NF-kB, estrogen receptor, progesterone receptor and prostaglandin receptor. Ann Med Surg (Lond) . 2021 Jun 17;67:102459.